[procaare] Re: SJS in HIV infection (1)

["Ann Marie Nelson" <procaare@usa.healthnet.org>]

Re: SJS in HIV infection (1)
- Ann Marie Nelson
************

<<Q: I would like to know if HIV+ have more chances of suffering from Drug induced
Stevens-Johnson Syndrome than HIV negative.>>

The answer to this question comes from experience and shared information, not actual
articles.
There does seem to be an increased risk of SJS related to some drugs in some HIV+
patients. In Africa, the use of Thiacetazone was associated with increased risk of SJS and
Lyles - reactions not seen as frequently in the general population. Neverapine can induce
SJS.

Maybe the immunologist out there might know if this is related to the B-cell stimulation,
HLA type or other factors.

Ann Marie Nelson, MD
Chief, Division of AIDS Pathology and Emerging Infectious Diseases
AFIP
E-mail: NELSONA@afip.osd.mil

--
To send a message to ProCAARE, write to: procaare@usa.healthnet.org
To subscribe or unsubscribe, write to: majordomo@usa.healthnet.org
in the body of the message type: subscribe procaare OR unsubscribe procaare
To contact a person, send a message to: procaare-help@usa.healthnet.org
Information and archives: http://www.procaare.org

The views presented in ProCAARE do not necessarily reflect the opinions of
SATELLIFE  (http://www.healthnet.org), the Harvard AIDS Institute
(http://aids.harvard.edu), or Health & Development Networks
(http://www.hdnet.org), unless otherwise stated. The reader assumes all
responsibilities in using information posted or archived by ProCAARE.
Reproduction is welcomed, provided ProCAARE and procaare@usa.healthnet.org
are quoted, and SATELLIFE is informed of usage.